The Lexington Hotel Washington, D.C. is located just off the Capital Beltway (Interstate 95/495), 1 mile from National Harbor and only 15 minutes from the White House..

From the South: Take I-95 North towards Baltimore. Cross over Woodrow Wilson Bridge. Take exit 3B (Route 210) Indian Head Highway South. Turn left at the light at top of Exit ramp onto Oxon Hill Road. Hotel located 1 block on the right.

 From the North: Take I-95/495 South towards Richmond, Virginia. Take Exit 3 (Route 210) Indian Head Highway South. Turn left at light, Oxon Hill Road. Hotel located 1 block on the right.